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Data from the Columbia University Department of Urology demonstrates that Zyflamend^®, a unique herbal extract preparation, suppresses the growth of prostate cancer cells and induces prostate cancer cells to self-destruct via a process called “apoptosis.”

The data, published in the October edition of Nutrition and Cancer, showed Zyflamend, a patented formulation from New Chapter^®, has the ability, in vitro, to reduce prostate cancer cell proliferation by as much as 78 percent and to induce cancer cell death or apoptosis.

The research confirms Zyflamend has COX-1 and COX-2 anti-inflammatory effects, although its anti-cancer affects against prostate cancer were independent of COX-2 inhibition, supporting the postulation that some prostate cancer cells are not affected by COX-2 inflammation.

“These results were particularly surprising and show great promise in the fight against prostate cancer,” said researcher Dr. Debra L. Bemis of the Columbia University Department of Urology. “We hope that the magnitude of benefits shown in this research will be confirmed in the larger scale trial already in progress.”

Based on this research, Zyflamend shows value in early therapy for prostate cancer patients. COX inhibitors have also shown value for prostate cancer patients, but data from recent trials of selective COX-2 inhibitors such as sulindac (Clinoril^®) and celecoxib (Celebrex^®), suggest that use of these drugs might have adverse cardiovascular effects. The more widely utilized general COX inhibitor, aspirin, is not associated with these negative side effects and, instead, has well-established beneficial effects for individuals with cardiovascular disease. Zyflamend has a biochemical action profile that resembles aspirin more than these selective COX-2 inhibitors.

Dr. Bemis added: “Zyflamend is derived from natural herbal sources and is readily available in health food and nutritional supplement stores. Given the impressive data we’re reporting, Zyflamend is a potentially more convenient and desirable means to target the enormous population that is susceptible to prostate cancer.”

On the strength of this laboratory research, Columbia University’s Department of Urology has commenced a Phase 1 human clinical trial testing Zyflamend’s ability to prevent prostate cancer in patients with prostatic intraepithelial neoplasia (PIN).

PIN is a clinical precursor for prostate cancer. Without intervention, men diagnosed with PIN have a 50 to 70 percent likelihood of developing prostate cancer. Although there are tools that detect the early signs of prostate cancer, such as PIN or elevated prostate specific antigen (PSA) levels, there is no consensus as to the optimal therapy for these patients.

“We are very encouraged about the early results of this phase 1 trial,” said Aaron E. Katz, M.D., associate professor of urology at Columbia University College of Physicians and Surgeons, Director of the Center of Holistic Urology at Columbia University Medical Center and principal investigator of the study.

“We are encouraged that this study provides additional scientific evidence that specific herbal preparations can produce a positive impact on prostate health,” said Mark Blumenthal, founder and executive director of the non-profit American Botanical Council. “With so many people using herbal supplements for their health, new research documenting their safety and benefits is encouraged and welcomed.”

Editor’s Note: The original news release can be found here.
Source: Columbia University Medical Center

http://www.sciencedaily.com/releases/2005/11/051112125637.htThis story has been adapted from a news release issued by Columbia University Medical Center. story has been adapted from a news release issued by Columbia University Medical Center.

You can purchase Zyflamend from your local health food store or from SMARTbomb.com

To Learn more about Zyflamend you can watch this video:

Building on the success of its #1 selling Vitamin C drink mix, Alacer Corp. announces the launch of Emergen-C Immune Defense^TM Formula, specially formulated to support a healthy immune system during the winter season.

For more than three decades, millions of loyal Emergen-C consumers have relied on Emergen-C’s potent blend of antioxidants, vitamins, minerals and other micronutrients to support healthy metabolic function and to naturally boost immunity and energy. “New Emergen-C Immune Defense takes our original formula one step further,” explains Tim Welch, President of Alacer Corp., “by adding enhanced zinc along with hibiscus extract and elderberry concentrate to stimulate the immune system.  The flavonoids in elderberry are thought to stimulate the immune system, and hibiscus has been used throughout the world to support the body’s natural defenses.  These added ingredients make new Emergen-C Immune Defense even more effective when our immune systems are severely challenged during the winter season.”

“With this enhanced formulation, along with the Emergen-C Immune Defense name, we wanted to create an Emergen-C product specifically designed for placement within the fast growing immune support segment of the cold and flu section of the grocery store,” adds Welch.

Emergen-C Immune Defense provides two distinct formulations, both with a soothing ruby lemon honey flavor - an effervescent drink mix which is added to water and a fizzing lozenge that slowly dissolves in the mouth without water.  Unlike other competing immune support products that require a glass of water for dissolving, the unique Emergen-C Immune Defense Lozenge requires no water but simply dissolves in the mouth, providing an ideal form for busy travelers who don’t always have easy access to water.  As Welch describes, “Now everyone can pop a lozenge on-the-go.  Our new Immune Defense Lozenge is the only immune support product designed to offer on-the-go convenience, plus the strength of our Emergen-C formula, containing enhanced zinc, hibiscus, and elderberry.”

 Available on SMARTbomb.com

We really didn’t cross a deep-water fish and a Valencia orange to develop our delicious, healthful Coromega® Omega-3 fatty acids supplement. But when you taste our exciting, new Omega-3 delivery system, we’re sure you’ll be amazed by the appetizing fresh orange taste.

Coromega’s exclusive production process transforms the pharmaceutical grade fish oil into a creamy, delicious pudding-like emulsion. We’ve made the experience of taking a fish oil supplement a pure pleasure by absolutely eliminating any fishy aftertaste. And, by adding a delicious orange flavor. The Coromega process and formulation, developed in Norway, was over 10 years in the making and is patented worldwide. This complex process assures the stability of the fish oil and the potency of the ingredients.

Coromega is a natural source of Omega-3 fatty acids from pharmaceutical grade fish oil. All impurities have been removed through a series of sophisticated processes, including molecular distillation, to provide a pure and concentrated source of Omega-3. Coromega is a proprietary emulsified form of Omega-3 fatty acids, EPA and DHA, protected and stabilized with vitamins C and E. Natural orange flavor. Naturally colored.

The Omega-3 and Omega-6 fatty acids make up two families of fats that are absolutely essential to human life. These essential fatty acids are important because they form important components of our cell membranes. They also regulate the body’s use of cholesterol and the production of substances that regulate nearly all other bodily processes.*

The body works best when the two types of fatty acids are combined in the right proportions. Because there is evidence that people in industrialized nations have a disproportionately high intake of Omega-6 fatty acids, it is suggested that we reduce our intake of Omega-6 and increase our intake of Omega-3. Daily supplementation with Coromega and reduced intake of Omega-6 fatty acids is a great way to seek a balance of these essential nutrients.

Historical Perspective

The Discovery of Omega-3 Essential Fatty Acids (EFAs)

Because EFA are essential for life and health, it is almost certain that the essential fatty acids (EFA) such as Omega-3, were here before mankind appeared on the planet. However, the discovery of essential fatty acids was delayed until the twentieth century, because there was no simple way to measure them. Extensive study of EFA did not occur until thin-layer chromatography was first applied to lipids at the University of Minnesota in the 1970s.*

A New Interest

In addition to the early pioneering research on essential fatty acids, increased interest in Omega-3 was generated by a study of the reasons why the Inuit people of Greenland were able to maintain healthy hearts and cardiovascular systems despite a diet that was rich in fat. The study revealed that although the Inuits’ diet was rich in fat from fish and sea mammals, it was also rich in marine Omega-3 fatty acids. Worldwide interest in Omega-3 grew with important research conducted by Sune K. Bergstrom, Bengti Samuelsson and Sir John R. Vane which earned them the 1982 Nobel Prize for their discoveries concerning prostaglandins and related biologically active substances. From this point the interest in Omega-3 has continued to grow with numerous studies on wide-ranging areas of health.*

Omega-3: The Lost Nutrient.

Today researchers estimate that around 80% of the sources of Omega-3 have disappeared from the food sources that make up our western diet. This means that unlike our Paleolithic ancestors whose diet was comprised of both the essential Omega-3 and Omega-6 fatty acids, in the right amounts, Omega-3 has rapidly become “the lost nutrient” in our diet. What was once a healthy balance of Omega-6 to Omega-3 in the human diet has become woefully out of balance. Although Omega-3 fatty acids are found in fresh cold-water fish such as mackerel, salmon and sardines, much of our foods have become laden with unhealthful “trans fats” by hydrogenation. To add to the problem, during the last ten to fifteen years, America decided to go “fat free”– in spite of the fact that thousands of studies suggest the importance of essential fatty acids in the diet. Coromega has been developed to support our Western diet, which is increasingly becoming stripped of essential Omega-3 fatty acids. It is a great way for our minds and bodies to get back the lost nutrient.

Coromega Delivers The Omega-3.

Coromega is an advanced Omega-3 essential fatty acids formula that delivers 650 mg of Omega-3, (similar to one small serving of salmon) including 350 mg of EPA and 230 mg of DHA, as well as Vitamins C & E and Folic Acid in each daily dose squeeze-pak. In addition to being a pleasure to take, Coromega’s delivery system ensures nutrient absorption.

Many Americans can remember, in the foggy mists of their memories, the moment they were administered their first dose of cod liver oil. The valuable nutrients, vitamin A and vitamin D, were the important reasons for taking this awful “caring spoonful” which was endearingly administered by a family care giver.

Surprisingly, the real nutritive value of this type of fish oil, was not discovered until the 1970’s when it was determined that certain fish oils contain the nutritional components, EPA (eicosapentaenoic acid) and DHA (docosahexaenoic acid). In fact, fish oil is the only Omega-3 source that features the metabolites of EPA and DHA. And these two super-unsaturates have now been found to have profound effects on both the cardiovascular system and also brain and eye function. Knowing the worthwhile nutritional benefits of fish oil, or more specifically, the Omega-3 fatty acids that reside within it, a tireless scientist embarked on a mission.

The scientist was intent on coming up with a formula that would mask fish oil’s very unpleasant odor and taste and thereby enable his granddaughter to want to take fish oil, with its nutritive Omega-3 properties. His young granddaughter, Monica, was at first the taste tester in his quest for a great tasting fish oil and then its greatest proponent. It is because of Monica that Coromega was discovered.

As the story is told, when Monica was growing up, she could not always avoid grandpa as he waited for her with a new fishy-tasting “caring spoonful” recipe. She was both her grandfather’s inspiration and his consumer acceptance audience. Therefore, it wasn’t always pleasant for Monica. Grandfather always had a new fish oil recipe and, at first, they all tasted badly.

Then one day, Monica’s grandfather created a product that he knew young Monica was sure to love. This time she could not believe that what she had pleasantly consumed was really Omega-3 rich fish oil. It tasted more like a confection, and there was absolutely no fishy taste or aftertaste.

The tireless scientist/grandfather had finally achieved his dream. He had at last created an Omega-3 supplement delicious enough for Monica. The innovative emulsion technology gained a worldwide patent in the early 1990s. And, after some ten years of trial and error, the loving grandfather had finally connected all the pieces. Great tasting Coromega was born.

 

For more information go to the Coromega Website or to purchase visit SMARTbomb.com